• Deakos

Bacterial biofilm

Biofilm is a particular biological structure formed by different bacterial and/or fungal species and of an extracellular matrix composed of mucopolysaccharides produced by them with high adhesive capacity. The biofilm can establish on an inert surface, such as a catheter or an intrauterine medical device, or on a living one, like a mucosa. Potential pathogenic microorganisms hide inside the biofilm, produce mucopolysaccharide matrix to hide, chronicize their persistence, protecting themselves from antibiotic attacks and immune defenses. In the deeper layers of biofilm, the low presence of oxygen and nutrients induces microbial cells to reduce their metabolism to become "quiescent", thus being even more resistant to drugs and immune defenses.

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