The term hematuria refers to the presence of blood in the urine. It may be so obvious to significantly change the color of the urine that therefore, it tends to become red / brown or may be less visible, but always detectable with sediment analysis when viewed under an optical microscope. The presence of blood in the urine can have different clinical meanings and may indicate changes in the kidneys and, therefore, we speak of glomerular or bladder, pelvic, urethral or prostatic hematuria. Bacterial cystitis is one of the main causes of bladder bleeding, especially when the bacterial load is high. In case of hematuria, it will be important to intervene quickly asking the specialist to verify the exact cause, before proceeding with the most appropriate and effective integrated therapy.